Medea Botanicals
Peppermint

Peppermint

Mentha piperita

Other names: Peppermint, Peppermint / garden mint, პიტნა, Mint / Peppermint & Spearmint, мята перечная (myata perechnaya)

Edible plant

Photo credit: Own work

This plant carries serious safety risks. All information is for educational reference only.

Safety information

Toxicity: Oral: heartburn, perianal burning, menthol odor in urine/stool; rare allergic reactions, bradycardia, tremor; anaphylaxis reported. Inhalation: apnoea, broncho-/laryngospasm in susceptible/allergic patients and in infants. | Culinary mint mild. The text itself warns: large doses of mint cause poisoning (and recommends grated carrot as antidote). See also wild mint / pennyroyal entry — FLAG. | Low at normal doses; menthol/concentrated oil are potent. Modern caution: do not apply menthol/oil to the face/nose of infants and young children (risk of laryngospasm); high oral oil doses can be irritant. | Mild. | None known reported. | Leaf/tea low toxicity. Peppermint oil can cause heartburn/relax lower-oesophageal sphincter; concentrated menthol oil not for infants (apnoea risk). | Mild. Oral oil can cause heartburn, nausea, abdominal pain, dry mouth; rare allergy. Topical oil can irritate skin.

Contraindications: Oral GI use contraindicated in achlorhydria, liver disease, gallstones/bile-duct obstruction. Not for children <8 (IBS) or <2 generally; cold/cough preparations not for children 2-11; topical headache use not <18 (EMA). Do not apply near face/nostrils of infants/young children. | Large doses; reflux (relaxes sphincter). | None specified by source. Modern: caution with reflux/hiatus hernia and in infants. | Do not give to children under 5; essential oil not for children under 12 without advice. | None specifically reported. | GERD/hiatus hernia (oil); infants/young children (menthol — do not apply to face). | Do not apply to the face/nose of infants/young children — menthol can cause reflex apnea. Caution with GERD/hiatal hernia (oil may relax LES). Food amounts likely safe in pregnancy; medicinal amounts not well studied.

Interactions: Caution with drugs reduced by gastric pH changes; theoretical inhibition of some CYP enzymes (e.g., CYP3A4) at high doses. | None documented in source. | None specified by source. | None specifically noted. | None reported. | Peppermint oil may inhibit CYP3A4 at high doses (theoretical). | Peppermint oil may inhibit CYP3A4 → may raise levels of some drugs (certain statins, calcium-channel blockers, cyclosporine) — theoretical/possible.

Pregnancy & breastfeeding: Not specifically addressed; age restrictions apply. | Used for nausea of pregnancy (traditional). | Food amounts likely safe; medicinal amounts not well studied.

Evidence level

Clinical

Supported by clinical trials in humans.

Preparations

This plant carries serious safety risks. All information is for educational reference only.

enteric capsules · leaves

Part used: leaves

Traditional use: irritable bowel syndrome

Evidence:Clinical
infusion · aerial parts

Part used: aerial parts

Traditional use: carminative/antispasmodic for flatulence, flatulent dyspepsia, intestinal colic; nausea, motion sickness, nausea of pregnancy; tension headaches

Proposed mechanism: stimulates bile and digestive juices

Evidence:Traditional (systematized)
inhalation · aerial parts

Part used: aerial parts

Traditional use: nasal catarrh

Evidence:Traditional (systematized)
edible raw/cooked (culinary) · leaf

Part used: leaf

Traditional use: culinary flavour(Folk and historical sources have not been validated by clinical research.)

Proposed mechanism: menthol

Evidence:Folk
infusion (tea) · leaf

Part used: leaf

Traditional use: digestive/carminative

enteric-coated essential-oil capsules · essential oil

Part used: essential oil

Traditional use: IBS-type abdominal pain/bloating

Proposed mechanism: menthol blocks intestinal smooth-muscle L-type calcium channels (antispasmodic), activates TRPM8/TRPA1; modulation of visceral hypersensitivity proposed

Dosage note (descriptive only): IBS trials commonly used enteric-coated capsules ~180-225 mg two to three times daily; descriptive only

Reference only — not a dosage instruction

Evidence:Clinical
topical 10% oil in ethanol · essential oil

Part used: essential oil

Traditional use: tension headache

Proposed mechanism: cooling/TRPM8 activation

Dosage note (descriptive only): 10% oil-in-ethanol applied to forehead/temples (EMA); descriptive only

Reference only — not a dosage instruction

Evidence:Clinical
infusion (leaf tea) / inhalation · leaf

Part used: leaf

Traditional use: cough/cold symptoms, localized muscle pain and itching

Dosage note (descriptive only): descriptive only

Reference only — not a dosage instruction

Evidence:Traditional (systematized)
infusion / juice / crushed leaf · leaf/aerial parts

Part used: leaf/aerial parts

Traditional use: speech disturbance (mint water in nose), nausea/vomiting (adults and children), digestion, urinary(Folk and historical sources have not been validated by clinical research.)

Dosage note (descriptive only): text warns large doses cause poisoning (grated carrot as antidote)

Reference only — not a dosage instruction

Evidence:Historical
Peppermint Water and Spirit (B.P.), essential oil, infusion/tea, menthol crystals · herb/oil

Part used: herb/oil

Traditional use: flatulence, colic, dyspepsia, abdominal cramp, nausea; prevent griping from purgatives; colds/influenza (with elder flower); topical menthol for neuralgia, rheumatism, headache, toothache, sea-sickness

Proposed mechanism: antispasmodic, stimulant, stomachic, carminative; modern: carminative/antispasmodic recognized (digestive spasm, IBS)

Dosage note (descriptive only): menthol/concentrated oil potent (small doses)

Reference only — not a dosage instruction

Evidence:Traditional (systematized)
infusion (tea) · leaves

Part used: leaves

Traditional use: digestive — relieves gas, bloating, colic, nausea, cramps, soothes colon; tension headaches/migraine; promotes sweating

Proposed mechanism: volatile oil strongly antibacterial; whole herb antispasmodic

Dosage note (descriptive only): not for children under 5

Reference only — not a dosage instruction

Evidence:Clinical
diluted essential oil / lotion · leaves

Part used: leaves

Traditional use: chest rub/inhalant

Dosage note (descriptive only): essential oil not for children under 12 without advice

Reference only — not a dosage instruction

Evidence:Clinical
enteric-coated oil capsules · aerial parts

Part used: aerial parts

Traditional use: irritable colon / ulcerative bowel conditions

Proposed mechanism: volatile oil mild anaesthetic to stomach wall

Dosage note (descriptive only): Commission E dosing

Reference only — not a dosage instruction

Evidence:Clinical
enteric-coated oil · oil

Part used: oil

Traditional use: IBS (medicinal)

Dosage note (descriptive only): GERD caution; not for infants (apnoea risk)

Reference only — not a dosage instruction

Evidence:Clinical
essential oil (enteric-coated capsules) · essential oil

Part used: essential oil

Traditional use: IBS symptoms and abdominal pain

Proposed mechanism: Gingerols not relevant; menthol; smooth-muscle relaxant

Dosage note (descriptive only): Recommended in 2021 ACG IBS guideline

Reference only — not a dosage instruction

Evidence:Clinical
infusion · leaves

Part used: leaves

Traditional use: indigestion, nausea, bloating, mild spasm, headache, mild calmative

Dosage note (descriptive only): Leaf evidence weaker than oil

Reference only — not a dosage instruction

Evidence:Traditional (systematized)

General preparation guide →

Associated conditions

Edibility

Edible parts: leaf (culinary - tea, flavoring). Concentrated essential oil is NOT a food. | Leaf raw/cooked, tea. | culinary flavouring, tea, confectionery | common culinary herb (tea, cooking), fresh or dried | culinary herb/flavoring | Leaf raw/cooked. | Leaves (raw in salads/drinks, or as tea); culinary flavoring.

Toxic lookalike warning

Low (aromatic). | Distinguish from Pennyroyal (Mentha pulegium) whose concentrated oil is toxic/abortifacient, and from other square-stemmed labiates when foraging. | Mints are mint-family (square stems, mint smell) and not generally confused with toxic plants; foragers should not confuse non-aromatic square-stemmed plants (some Lamiaceae) — confirm the strong mint scent. Avoid pennyroyal (Mentha pulegium), a true mint whose oil (pulegone) is hepatotoxic/abortifacient — FLAGGED. | When foraging mints, do not mistake for pennyroyal (Mentha pulegium), whose oil is hepatotoxic and abortifacient — confirm by scent and positive ID.

Nutritional notes

Leaf used as flavoring/tea; negligible nutrition. | Flavouring; aids digestion; negligible nutritional value. | Culinary herb. | Culinary aromatic. | Menthol, rosmarinic acid, vitamin A; low-calorie functional culinary herb. | Leaf low-calorie; small amounts of vitamin A, manganese, antioxidants (rosmarinic acid); mainly a flavoring.

Healing traditions

Sources (13)

  1. Grieve M., A Modern Herbal (1931)Maud Grieve (1931)
  2. Chevallier A., Encyclopedia of Herbal Medicine (2016)Andrew Chevallier (2016)
  3. Hoffmann D., Medical Herbalism (2003)David Hoffmann (2003)
  4. Mtsire Karabadini, Part II (Surmanidze, 1990)Ramaz Surmanidze (1990)
  5. Karabadini (Khelaia ed., 2009)Nani Khelaia (ed.) (2009)
  6. EMA/HMPC Menthae piperitae aetheroleum monograph & public summary
  7. Linas 2026 Menthacarin phase IV trial (PMID 41405807, DOI 10.1007/s10354-025-01119-2)
  8. Pastras 2026 plant-derived IBS treatments review (PMID 41599795, DOI 10.3390/nu18020183)
  9. EMA/HMPC Menthae piperitae aetheroleum (peppermint oil)
  10. NCCIH peppermint information
  11. Peppermint Oil: Usefulness and Safety — NCCIH/NIH, 2025
  12. Ingrosso MR et al., Aliment Pharmacol Ther 2022;56(6):932-941 (PMID 35942669)
  13. Lacy BE et al., Am J Gastroenterol 2021;116(1):17-44 (PMID 33315591)

All sources →

Not medical advice. Consult a qualified healthcare professional before using any plant or preparation.