
Cat's-claw / gou teng (钩藤)
Uncaria rhynchophylla
Photo credit: keisotyo
Safety information
Safety information
Toxicity: Low at traditional doses; should be decocted briefly.
Contraindications: TCM caution where no wind/heat pattern; pregnancy data limited.
Interactions: Possible additive hypotensive effect; CNS-active alkaloids -> caution with sedatives/antihypertensives.
Pregnancy & breastfeeding: Pregnancy data limited.
Evidence level
Supported by laboratory or animal studies; not yet confirmed in humans.
Preparations
in formula (Tian Ma Gou Teng Yin) · hooked stem/twigs
Part used: hooked stem/twigs
decoction (added late — heat-sensitive alkaloids) · hooked stem/twigs
Part used: hooked stem/twigs
Traditional use: extinguishes wind, calms the liver, clears heat; convulsions, childhood febrile fits, hypertension-type dizziness/headache, eclampsia
Proposed mechanism: indole/oxindole alkaloids (rhynchophylline, isorhynchophylline) — antihypertensive, anticonvulsant, neuroprotective
Dosage note (descriptive only): decoct briefly
Associated conditions
Nutritional notes
n/a
Healing traditions
Sources (2)
- [E11] rhynchophylline antihypertensive/neuroprotective study
- [E10] Uncaria rhynchophylla CNS pharmacology review