Medea Botanicals
Jiaogulan / southern ginseng

Jiaogulan / southern ginseng

Gynostemma pentaphyllum

Other names: 绞股蓝 / 絞股藍 jiǎogǔlán, Jiaogulan / southern ginseng

Edible plant
Chinese

Photo credit: Frank Vincentz

Safety information

Safety information

Toxicity: Generally low-toxicity as a tea; some reports of nausea/loose stools at higher doses; comprehensive human safety data limited.

Contraindications: Pregnancy/clinical data limited; caution combining with antidiabetic and antihypertensive drugs; theoretical antiplatelet caution.

Interactions: Possible additive effects with antidiabetic, antihypertensive, and anticoagulant/antiplatelet drugs.

Pregnancy & breastfeeding: Data limited.

Evidence level

Clinical

Supported by clinical trials in humans.

Preparations

infusion · leaf

Part used: leaf

Traditional use: qi-tonic for fatigue, cough, longevity; caffeine-free adaptogenic tea

Proposed mechanism: gypenosides (saponins related to ginsenosides), flavonoids

Evidence:Preclinical
decoction/extract · aerial herb

Part used: aerial herb

Traditional use: metabolic/lipid, AMPK-related (lab/animal/small human)

Proposed mechanism: gypenosides

Evidence:Clinical

General preparation guide →

Associated conditions

Edibility

Edible parts: Leaves used as herbal tea/infusion (principal traditional use); young shoots eaten as a vegetable in some regions.

Toxic lookalike warning

A five-leaflet climbing vine that can resemble other cucurbit/vine plants; use only authenticated Gynostemma, as some wild vines and their fruits are toxic.

Nutritional notes

Functional tea; gypenoside saponins, flavonoids; negligible macronutrient.

Healing traditions

Chinese
Sources (2)

  1. Gynostemma pentaphyllum (Wikipedia), English, accessed 2026, https://en.wikipedia.org/wiki/Gynostemma_pentaphyllum
  2. Jiaogulan / Gynostemma - Drugs.com natural database, English, https://www.drugs.com/npp/gynostemma.html

All sources →

Not medical advice. Consult a qualified healthcare professional before using any plant or preparation.